abstract：BACKGROUND AND AIMS:To explore hepatoprotective action of curcumin (CMN, a bioflavonoid) on oxaliplatin (Oxa)-triggered mitochondrial oxidative stress and respiratory chain complexes in liver of rats. Oxa is a ubiquitously utilized platinum-based chemotherapeutic agent commonly used for the treatment of colorectal canc...

journal_title：Archives of medical research

authors： Waseem M,Parvez S,Tabassum H

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Childhood acute lymphoblastic leukemia (ALL) is the leading cause of childhood cancer-related deaths worldwide. Multiples studies have shown that ALL seems to be originated by an interaction between environmental and genetic susceptibility factors. The ARID5B polymorphisms are among the most reprodu...

journal_title：Archives of medical research

authors： Bekker-Méndez VC,Núñez-Enríquez JC,Torres Escalante JL,Alvarez-Olmos E,González-Montalvoc PM,Jiménez-Hernández E,Sansón AM,Leal YA,Ramos-Cervantes MT,Guerra-Castillo FX,Ortiz-Maganda MP,Flores-Lujano J,Pérez-Saldivar ML,Velazqu

更新日期：2016-11-01 00:00:00

abstract：:Type 2 diabetes (T2D) is a complex disease caused by the interaction of genetic and environmental factors. In this regard, it has been demonstrated that Hispanics have a greater susceptibility to developing complex diseases like T2D, which has been attributed to their Amerindian component. Mexico has a wide population...

journal_title：Archives of medical research

authors： Sánchez-Pozos K,Menjívar M

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Transport of membranes and proteins in eukaryotic cells is mediated by vesicular carriers. Coatomer complex I (COPI)-coated vesicles are involved in the transport between endoplasmic reticulum (ER) and Golgi complex. Several studies indicated that some subunits of COPI were correlated with the cell ...

journal_title：Archives of medical research

authors： Mi Y,Yu M,Zhang L,Sun C,Wei B,Ding W,Zhu Y,Tang J,Xia G,Zhu L

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Bacteremia is a common serious manifestation of disease in the intensive care unit (ICU), which requires quick and accurate determinations of pathogens to select the appropriate antibiotic treatment. To overcome the shortcomings of traditional bacterial culture (BC), we have adapted next-generation ...

journal_title：Archives of medical research

authors： Long Y,Zhang Y,Gong Y,Sun R,Su L,Lin X,Shen A,Zhou J,Caiji Z,Wang X,Li D,Wu H,Tan H

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers in developing countries. The aim of the study was to determine the association between serum CD26 concentration and outcome of patients with ESCC. METHODS:A total of 183 patients with ESCC and 254 healthy controls were selected. Blo...

journal_title：Archives of medical research

authors： Xinhua W,Xiangting Q,Lingling C,Guohong L

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Intestinal microbiota and soluble dietary fiber play an important role in intestinal microecology, which is closely related to gut motility. Regulating intestinal microecology comprised of fecal microbiota transplantation (FMT) or fiber supplementation is becoming a novel therapy for functional gast...

journal_title：Archives of medical research

authors： Ge X,Tian H,Ding C,Gu L,Wei Y,Gong J,Zhu W,Li N,Li J

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND AIMS:As a newly discovered B-cell subset, PDCA-1(+) B cells have been shown to participate in the immune clearance of invading pathogens. The prominence of PDCA-1(+) B cell immunity in the pathogenesis of Helicobacter pylori infection prompted us to explore the potential role of this subset in gastric H....

journal_title：Archives of medical research

authors： Ma Z,Liu G,Zhang M,Li M,Liu Y,Yanfang J

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Small cell lung cancer (SCLC) is frequently associated with syndrome of inappropriate antidiuretic hormone (SIADH) secretion. In this study we investigated the prognostic value of SIADH in Chinese patients with SCLC. METHODS:We prospectively studied a total of 385 patients with SCLC diagnosed in ou...

journal_title：Archives of medical research

authors： Wang X,Liu M,Zhang L,Ma K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The present study analyzed the relationship between TP53 codon 72 polymorphisms and the clinical outcome of advanced gastric cancer patients receiving capecitabine plus paclitaxel chemotherapy. METHODS:Three hundred patients with advanced gastric cancer treated with paclitaxel and capecitabine comb...

journal_title：Archives of medical research

authors： Zha Y,Gan P,Liu Q,Yao Q

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Few studies have described the association between hepcidin levels and cardiometabolic risk in the general population and more so by considering robust adjustment for confounding factors. Therefore, the aim of the present study was to investigate the associations between circulating hepcidin and ant...

journal_title：Archives of medical research

authors： Suárez-Ortegón MF,Arbeláez A,Mosquera M,Moreno-Navarrete JM,Aguilar-Plata C,Fernández-Real JM

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Metabolic syndrome (MetS) is a disorder that includes a cluster of several risk factors for the development of type 2 diabetes and cardiovascular disease. The R230C variant of the ABCA1 gene has been associated with low HDL-cholesterol in several studies, but its association with MetS in children re...

journal_title：Archives of medical research

authors： Gamboa-Meléndez MA,Galindo-Gómez C,Juárez-Martínez L,Gómez FE,Diaz-Diaz E,Ávila-Arcos MA,Ávila-Curiel A

更新日期：2015-08-01 00:00:00

abstract：:Cardiovascular disease (CVD) is a universal problem in modern society. Atherosclerosis is the leading cause of CVD resulting in high rate of mortality in the population. Nutrition science has focused on the role of essential nutrients in preventing deficiencies, at the present time, the nutritional strategies are cruc...

journal_title：Archives of medical research

authors： Torres N,Guevara-Cruz M,Velázquez-Villegas LA,Tovar AR

更新日期：2015-07-01 00:00:00

abstract：:Metabolic syndrome (MetS) should be considered a clinical entity when its different symptoms share a common etiology: obesity/insulin resistance as a result of a multi-organ dysfunction. The main interest in treating MetS as a clinical entity is that the addition of its components drastically increases the risk of ath...

journal_title：Archives of medical research

authors： Luna-Luna M,Medina-Urrutia A,Vargas-Alarcón G,Coss-Rovirosa F,Vargas-Barrón J,Pérez-Méndez Ó

更新日期：2015-07-01 00:00:00

abstract：:Atherosclerosis together with multiple sclerosis, psoriasis and rheumatoid arthritis can be used as examples of chronic inflammatory diseases associated with multifactorial components that evolve over the years. Nevertheless, an important difference between these diseases relies on the fact that atherosclerosis develo...

journal_title：Archives of medical research

authors： García-González V,Delgado-Coello B,Pérez-Torres A,Mas-Oliva J

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Patients with certain types of stroke need urgent anticoagulation and it is extremely important for them to achieve fast and stable anticoagulant effect and receive individualized treatment during the initiation of warfarin therapy. METHODS:We conducted a prospective study among 210 acute stroke patients wh...

journal_title：Archives of medical research

authors： Šupe S,Poljaković Z,Božina T,Ljevak J,Macolić Šarinić V,Božina N

更新日期：2015-05-01 00:00:00

abstract：:The number of patients requiring lung transplantation is increasing, with a significant unmet demand for grafts. Ex vivo lung perfusion has been developed to increase graft recruitment. The major complications of lung transplantation include chronic allograft dysfunction (CLAD) whose cumulative incidence ranges from 4...

journal_title：Archives of medical research

authors： Mohamed MS

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Streptococcus pneumoniae is the leading cause of acute otitis media, pneumonia, meningitis, and sepsis. The heptavalent pneumococcal conjugate vaccine (PCV7) was incorporated into the national immunization program in Mexico in 2008. The aim of the study was to analyze the frequency of S. pneumoniae ...

journal_title：Archives of medical research

authors： Echaniz-Aviles G,Soto-Nogueron A,Miranda-Novales G,Carnalla-Barajas MN,Velazquez-Meza ME,Solórzano-Santos F,SIREVA Network–Mexico.

更新日期：2015-02-01 00:00:00

abstract：:It is likely that monosodium glutamate (MSG) is the excitotoxin that has been most commonly employed to characterize the process of excitotoxicity and to improve understanding of the ways that this process is related to several pathological conditions of the central nervous system. Excitotoxicity triggered by neonatal...

journal_title：Archives of medical research

authors： Gudiño-Cabrera G,Ureña-Guerrero ME,Rivera-Cervantes MC,Feria-Velasco AI,Beas-Zárate C

更新日期：2014-11-01 00:00:00

abstract：:Blood-brain barrier (BBB) disruption has been associated with several acute and chronic brain disorders such as Alzheimer's disease, Parkinson's disease and epilepsy. This represents a critical situation because damaged integrity of the BBB is related to the influx of immune mediators, plasma proteins and other outsid...

journal_title：Archives of medical research

authors： Bañuelos-Cabrera I,Valle-Dorado MG,Aldana BI,Orozco-Suárez SA,Rocha L

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND AIMS:T-helper (Th) cells involved in the pathogenesis of multiple sclerosis (MS) represent a functionally heterogeneous population defined by their cytokine secretion profile. The effects of immunotherapeutic drugs on the cytokine network are still not fully clarified. This study aimed to investigate ser...

journal_title：Archives of medical research

authors： Trenova AG,Slavov GS,Manova MG,Kostadinova II

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The pathogenesis of coronary artery ectasia (CE) is poorly understood. An underlying inflammatory process is suspected; current therapy aims to prevent thrombotic events. Presently, there is no evidence to support an anti-inflammatory approach for CE patients. We undertook this study to determine th...

journal_title：Archives of medical research

authors： Soto ME,Reyes-Villatoro MA,Márquez R,Cardoso G,Posadas-Sánchez R,Juárez-Orozco LE

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND AIMS:In this study, we aimed to investigate whether 1800 MHz frequency electromagnetic radiation (EMR) has an effect on bone healing. METHODS:A total of 30 Wistar albino rats were divided into two equal groups. Fractures were created in the right tibias of all rats; next, intramedullary fixations with K...

journal_title：Archives of medical research

authors： Aslan A,Kırdemır V,Kocak A,Atay T,Baydar ML,Özerdemoglu RA,Aydogan NH

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Monocyte chemotactic protein-1 (MCP-1) gene polymorphisms play important roles in regulating immunological reactions and may be associated with pulmonary tuberculosis. However, the relationship between the MCP-1 -2518 gene polymorphism and susceptibility to spinal tuberculosis remains unknown. We un...

journal_title：Archives of medical research

authors： Gao Q,Du Q,Zhang H,Guo C,Lu S,Deng A,Tang M,Liu S,Wang Y,Huang J,Guo Q

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Thyroid hormones exert important effects on heart remodeling through mir-208. The process may have a role in myocardial changes in chronic kidney disease where thyroid abnormalities are common. In this study the effect of T4 supplementation on left ventricle (LV) remodeling in 5/6 nephrectomized rat...

journal_title：Archives of medical research

authors： Prado-Uribe MD,Soto-Abraham MV,Mora-Villalpando CJ,Gallardo JM,Bonilla E,Avila M,Tena E,Paniagua R

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The use of automated peritoneal dialysis (APD) is increasing compared to continuous ambulatory peritoneal dialysis (CAPD). Surprisingly, little data about health benefits and cost of APD exist, and virtually no information comparing the cost-utility between CAPD and APD is available. We undertook th...

journal_title：Archives of medical research

authors： Cortés-Sanabria L,Paredes-Ceseña CA,Herrera-Llamas RM,Cruz-Bueno Y,Soto-Molina H,Pazarín L,Cortés M,Martínez-Ramírez HR

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Despite its beneficial effects, cisplatin has considerable nephrotoxic, ototoxic, neurotoxic and hepatotoxic side effects. It has been documented that reactive oxygen radical species are involved with the pathophysiology of cisplatin-induced hepatotoxicity. Molsidomine (MOL) can exert antioxidant an...

journal_title：Archives of medical research

authors： Bentli R,Parlakpinar H,Polat A,Samdanci E,Sarihan ME,Sagir M

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Various studies have reported a direct association of cervical cancer risk with obesity and weight but not with the body fat percentage (BFP). The aim of this study was to analyze various anthropometric measures as potential risk factors for cervical cancer. METHODS:A total of 20,236 women were inc...

journal_title：Archives of medical research

authors： López-Hernández D

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND AIMS:We tested the effects of recombinant insulin-like growth factor-I (IGF-I) in an adipocyte model of HIV lipodystrophy and in an open label study on body composition and metabolism in patients with HIV lipodystrophy. METHODS:The effects of IGF-I on ritonavir-induced adipocyte cell death were studied ...

journal_title：Archives of medical research

authors： Kim RJ,Vaghani S,Zifchak LM,Quinn JH,He W,Tebas P,Frank I

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND AIMS:To compare the prevalence of lactose malabsorption (LM) in children by analyzing hydrogen content in expired air vs. the inclusion of methane excretion. METHODS:A total of 138 children (4-17 years old) attending different boarding schools in Mexico were included in this study. To measure H₂ and CH₄...

journal_title：Archives of medical research

authors： Moran S,Mina A,Duque X,Anaya S,San-Martin U,Yañez P,Rodriguez-Leal G

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND AIMS:The major limiting factor in therapeutic application of mesenchymal stem cells (MSCs) is their high vulnerability during the early days of transplantation. Hence, researchers have been encouraged to find various strategies to make the cells resistant to different stresses before and after transplant...

journal_title：Archives of medical research

authors： Kiani AA,Kazemi A,Halabian R,Mohammadipour M,Jahanian-Najafabadi A,Roudkenar MH

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The efficacy of a direct application of plasma needle to in vivo wound healing was experimentally studied in mice. This kind of plasma has achieved considerable success in blood coagulation and tissue restoration in mice. In the development of the present study, an argon plasma needle was chosen for...

journal_title：Archives of medical research

authors： García-Alcantara E,López-Callejas R,Morales-Ramírez PR,Peña-Eguiluz R,Fajardo-Muñoz R,Mercado-Cabrera A,Barocio SR,Valencia-Alvarado R,Rodríguez-Méndez BG,Muñoz-Castro AE,de la Piedad-Beneitez A,Rojas-Olmedo IA

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIMS:An increasing number of studies have been published concerning meeting targets of clinical guidelines for different aspects of the diagnosis and treatment of patients with end-stage renal disease. Most of these studies have shown that guideline recommendations are not always satisfied, and results o...

journal_title：Archives of medical research

authors： Paniagua R,Ventura MD,Ávila-Díaz M,Hinojosa-Heredia H,Méndez-Duran A,Cisneros A,Gómez AM,Cueto-Manzano A,Trinidad P,Obrador GT,García-López E,Lindholm B

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Streptococcus pneumoniae constitutes one of the main causes of sepsis, bacteremia and meningitis (pneumococcal invasive disease - PID), and pneumonia in infants and small children. Antipneumococcal vaccination in Mexico is expected to be a useful strategy to reduce morbimortality due to this cause. ...

journal_title：Archives of medical research

authors： Bautista-Márquez A,Richardson V,Ortiz-Orozco O,Luna-Cruz ME,Carnalla-Barajas MN,Echaniz-Avilés G,Bobadilla-del Valle M,Martínez-Medina L,Montalvo-Vázquez AM,de la Re-Montaño N,Anchondo-Martínez I,Tinoco-Favila JC,Martínez-Aguilar

更新日期：2013-02-01 00:00:00

abstract：:The expression of neurodegenerative diseases can be categorized into three main symptomatic domains: neurological, cognitive and, neuropsychiatric. This review focuses on the cognitive profile and neuropsychological assessment of Alzheimer's disease (AD). The topography and progression of brain neuropathology determin...

journal_title：Archives of medical research

authors： Peña-Casanova J,Sánchez-Benavides G,de Sola S,Manero-Borrás RM,Casals-Coll M

更新日期：2012-11-01 00:00:00

abstract：:Alzheimer's disease (AD) diagnosis still depends on the triad of clinical, imaging and neuropsychological testing. The development of accurate, easy to use and inexpensive biological markers for AD is a long-standing aspiration for researchers and the medical community. Here we describe some of the recent advances in ...

journal_title：Archives of medical research

authors： Guzmán-Martínez L,Farías GA,Maccioni RB

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND AIMS:In Brazil, sickle cell anemia (SCA) is one of the most common genetic disorders. The levels of fetal hemoglobin (HbF) may be influenced by the presence of genetic modifiers; among these are the β(S)-globin haplotypes, associated with the clinical heterogeneity presented by the disease. Patients with...

journal_title：Archives of medical research

authors： Carvalho-dos Santos BS,Dias-Elias DB,da Silva-Rocha LB,Cavalcante-Barbosa M,Pinheiro-Gonçalves R

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND AND AIMS:MicroRNA-34a (miR-34a) as a tumor suppressor has been reported in many other studies. However, its role in modulating the sensitivity of breast cancer cells to adriamycin (ADR) remains unclear. The aim of this study is to evaluate the role of miR-34a in the sensitivity of breast cancer cells to ADR....

journal_title：Archives of medical research

authors： Li XJ,Ji MH,Zhong SL,Zha QB,Xu JJ,Zhao JH,Tang JH

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Phosphodiesterases 5 and 9 (PDE5, PDE9) are enzymes responsible for regulating second messenger signaling by hydrolyzing 3',5' cyclic guanosine monophosphate (cGMP). PDE isoforms are deregulated in some types of human cancer. The present study was carried out to evaluate the expression of phosphodie...

journal_title：Archives of medical research

authors： Karami-Tehrani F,Moeinifard M,Aghaei M,Atri M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND AND AIMS:We undertook this study to assess the effects of omega-3 polyunsaturated fatty acids (PUFAs) (administered at ≥2.7 g/day) for a minimum duration of 3 months on clinical outcomes in patients with rheumatoid arthritis (RA). METHODS:The authors surveyed randomized controlled trials (RCTs) that examine...

journal_title：Archives of medical research

authors： Lee YH,Bae SC,Song GG

更新日期：2012-07-01 00:00:00